Natural neurotransmitter optimization for healthy brain
What are neurotransmitters?
Let’s relate them to hormones; most of you are familiar with hormones. You know if your hormones are low, you can balance them by taking personalized Bioidentical Hormone Replacement Therapy.. Hormones are the chemical messengers by which the endocrine system communicates, or talks. Similarly neurotransmitters are the way our nervous system communicates between the central nervous system to the end or target organs. If you don’t have balanced neurotransmitters, you don’t feel good, just like if you don’t have enough hormones, you don’t feel right. The core system of our body consists of Neuro-Endocrine Immune Axis. We are as old as these systems get. If they are in sync and balanced appropriately the aging process slows down. All the systems of our body are supposed to talking to each other with the help of the Neuro Endocrine and Immune axis using Neurotransmitters, hormones and immune mediators.
How do antidepressants work?
To know how the antidepressants work its important to know the mechanism of the neurotransmitters functions. Neurotransmitters are stored in the presynaptic vesicles or storage bubbles of neuronal ending which gets message from the brain. They stay in this location till they are needed or a signal is received from the brain. Once the impulse arrived from previous neuron or the central nervous system it will induce the rupture of these vesicles and releasing the neurotransmitters in the space between the two nerve endings filling the gap and making the two nerves connection complete hence traveling the impulse from one end to the other like an electrical cable.
If our bodies lack the necessary amino acids responsible to produce these neurotransmitters we will not have enough of storage form in the pre synaptic nerve ending and thus there will not be enough release of them in the space between two nerves endings which we call synapse. So the space will not have enough neurotransmitters and the message cannot propagate eventually causing the symptoms of feeling low or depression.
Anytime the neurotransmitters go into this synaptic cleft they either reabsorbed by the previous neurons, some of them have the effect, some float away, some are broken down, and some are recycled. When they have their effect that is how your nervous system is communicating. Then they get sucked back up with the help of reuptake transporter and used again in the future, because not all of them make it across and have an effect, and your body is trying to be efficient and save them for next time so you don’t have to work as hard to make more. If you don’t have enough, the antidepressant medications like selective serotonin reuptake inhibitors SSRI will turn off the recycling and increasing the local concentration in the synaptic cleft resulting in the happy feel good mood. Well if you aren’t recycling them, the Neurotransmitters are going to stay in the synapse longer even longer, and have a better chance of having the effect on the other side.Read more about Brain Antiaging